Properties of choline esterase in human serum
نویسندگان
چکیده
منابع مشابه
Lxxii. Properties of Choline Esterase in Human Serum
THE importance of the physiologically active substance acetylcholine makes it highly desirable that the properties of the enzyme which specifically hydrolyses choline esters be established. Summaries of the past work on this enzyme have recently appeared [Ammon, 1935; Gaddum, 1935; Oppenheimer, 1935]. It is remarkable that although choline esterase has been studied in relation to its partial pu...
متن کاملThe Choline-esterase Activity of the Blood Serum in Disease.
The investigations of Dale and his coworkers (1, 2) on the chemical transmission of parasympathetic nerve stimulation and of Walker (3, 4) on the use of physostigmine and prostigmin in myasthenia gravis have stimulated interest in the choline-esterase activity of serum. Lucas, Hall, and Ettinger (5) studied the serum esterase activity of 200 subjects and obtained results that were in essential ...
متن کاملCcl. the Relative Choline-esterase Activities of Serum
FOLLOWING the discovery by Stedman et al. [1932] that the destruction of acetylcholine by blood serum was brought about by a specific enzyme, which they termed choline-esterase, Stedman et al. [1933] examined the blood sera from a number of species for the presence of this enzyme and compared the cholineesterase activities of these sera with their activities towards two other types of esters, n...
متن کاملStudies on the Specificity of Choline Esterase
The present investigation was undertaken to determine the relation between the structure of various substrates and the action of serum choline esterase upon them. The comparison of activities with different esters should take into account two factors : the hydrolytic velocities compared should be linear functions of time, and these velocities should be independent of substrate concentration. Th...
متن کاملOn The Physiological Significance of Choline Esterase *
During the last 20 years evidence has accumulated, mainly from the work of 0. Loewi, Dale, Cannon and their co-workers, supporting the view that the action of sympathetic and parasympathetic nerves on the effector organ occurs by virtue of chemical mediation. It is generally believed that adrenaline, or a related substance, sympathin, is the transmitter substance at sympathetic nerve endings, w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1937
ISSN: 0306-3283
DOI: 10.1042/bj0310521